NAPLEX Blueprint

The NAPLEX Competency Statements provide a blueprint of the topics covered on the examination. They offer important information about the knowledge, judgment, and skills you are expected to demonstrate as an entry-level pharmacist. A strong understanding of the Competency Statements will aid in your preparation to take the examination.

In July 2014, a committee of subject matter experts reviewed the current statements and revised them to fit the most current standards for safe and effective pharmacy practice. The new Competency Statements went into effect on November 1, 2015. Learn more about the revision process.

Competency Statements

AREA 1 – Ensure Safe and Effective Pharmacotherapy and Health Outcomes (Approximately 67% of Test)

1.1.0 Obtain, Interpret, Assess, and/or Evaluate:

  • 1.1.1 Information from patient interviews
  • 1.1.2 Patient medical records
  • 1.1.3 Results from instruments and screening strategies used to assess patients
  • 1.1.4 Laboratory and diagnostic findings
  • 1.1.5 Signs and symptoms associated with diseases and medical conditions
  • 1.1.6 Patients’ need for medical referral
  • 1.1.7 Risk factors relevant to the prevention of a disease or medical condition and the maintenance of wellness
  • 1.1.8 Information from interdisciplinary health care providers

1.2.0 Develop and Implement Individualized Treatment Plans, Taking Into Consideration:

  • 1.2.1 Specific uses and indications and dosing for drugs
  • 1.2.2 Purported uses and indications for dietary supplements and complementary and alternative medicine
  • 1.2.3 Lifestyle and self-care therapy
  • 1.2.4 Pharmacologic classes and characteristics of drugs
  • 1.2.5 Actions and mechanisms of actions of drugs
  • 1.2.6 The presence of pharmacotherapeutic duplications and/or omissions
  • 1.2.7 Drug interactions
  • 1.2.8 Contraindications, warnings, and precautions
  • 1.2.9 Allergies
  • 1.2.10 Adverse effects and drug-induced illness
  • 1.2.11 Pharmacodynamic, pharmacokinetic, and pharmacogenomic principles
  • 1.2.12 Pharmacokinetic data to determine equivalence among drug products
  • 1.2.13 Pharmacoeconomic factors
  • 1.2.14 Routes and methods of administration, dosage forms, and delivery systems

1.3.0 Assess and Modify Individualized Treatment Plans, Considering:

  • 1.3.1 Therapeutic goals and outcomes
  • 1.3.2 Safety of therapy
  • 1.3.3 Efficacy of therapy
  • 1.3.4 Medication non-adherence or misuse

1.4.0 Techniques for Effective Communication/Documentation of the Development, Implementation, and Assessment of Individualized Treatment Plans to:

  • 1.4.1 Patients and/or patients’ agents
  • 1.4.2 Interdisciplinary health care providers

1.5.0 Advocate Individual and Population-Based Health and Safety, Considering:

  • 1.5.1 Best practices, scientific literature evaluation, and health-related resources
  • 1.5.2 Quality improvement strategies in medication-use systems
  • 1.5.3 Processes, evaluation of, and responses regarding medication errors
  • 1.5.4 Role of automated systems and technology in medication distribution processes
  • 1.5.5 Emergency preparedness protocols

AREA 2 – Safe and Accurate Preparation, Compounding, Dispensing, and Administration of Medications and Provision of Health Care Products (Approximately 33% of Test)

2.1.0 Employ Various Techniques to Calculate:

  • 2.1.1 Patients’ nutritional needs and the content of nutrient sources
  • 2.1.2 Drug concentrations, ratio strengths, and/or extent of ionization
  • 2.1.3 Quantities of medication to be compounded, dispensed, or administered
  • 2.1.4 Quantities of ingredients needed to compound preparations
  • 2.1.5 Rates of administration

2.2.0 Compound Sterile and Nonsterile Products, Considering:

  • 2.2.1 Techniques, procedures, and equipment for drug preparation, compounding, and administration of sterile products
  • 2.2.2 Techniques, procedures, and equipment for drug preparation, compounding, and administration of nonsterile products
  • 2.2.3 Physicochemical properties of active and inactive ingredients
  • 2.2.4 Identifying the presence of, and the cause of, product incompatibilities or degradation and methods for achieving stability
  • 2.2.5 Physiochemical properties of drugs that affect solubility and stability

2.3.0 Review, Dispense, and Administer Drugs and Drug Products, Considering:

  • 2.3.1 Packaging, labeling, storage, handling, and disposal of medications
  • 2.3.2 Commercial availability, identification, and ingredients of prescription and non-prescription drugs
  • 2.3.3 Physical attributes of drug products
  • 2.3.4 Specific instructions and techniques for administration